Phagocyte definition and meaning collins english dictionary. Phagocytosis occurs after the foreign body, a bacterial cell, for example, has bound to molecules called receptors that are on the surface of the phagocyte. Phagocytosis of iggopsonized particles phospholipase d. It engulfs foreign bodies by extending its cytoplasm into pseudopods cytoplasmic extensions like feet, surrounding the foreign particle and forming a vacuole. Aggiornamenti di medicina e chirurgia phagocytic index. Advances in cellular and molecular biology of membranes and. After intravenous administration, the phagocytic index of peritoneal macrophages was 6. Phagocytic index definition of phagocytic index at.
Phagocyte definition of phagocyte by medical dictionary. Number of phagocyting pmnl in % is determining the phagocytosis or phagocytic activity. Phagocytic index definition of phagocytic index by the. Apoptotic cells protein is required for efficient phagocytosis of. Chapter 14 measuring the phagocytic activity of cells.
The phagocytic index was calculated according to the following formula. Phagocytic capacity of leucocytes in sheep mammary. Trem2 regulates microglial cholesterol metabolism upon. The individual is scored in a number of areas depending upon independence of performance. In this scanning electron micrograph sem, one can see the early stages of phagocytosis of a yeast particle y by a leukocyte. This is the value of functional properties of phagocytes. Phagocytic definition, any cell, as a macrophage, that ingests and destroys foreign particles, bacteria, and cell debris. We performed the following procedures in spraguedawley rats. Phagocytic index financial definition of phagocytic index. The average number of apoptotic particles per macrophage phagocytic index was calculated per embryo by dividing the total number of apoptotic particles inside labeled macrophages by the number of. We investigated splenic reticuloendothelial activity after splenic preservation procedures to determine their effect upon the phagocytic function of the spleen. Catholics are forbidden, as a natural part of ethics, to read anything they know may endanger their faith or moral life. Phagocytosis is one of the first reactions of many cells in the body in response to the.
The cell membrane of the phagocyte forms fingerlike. Pdf effects of cell differentiation on the phagocytic. Critical role of galectin3 in phagocytosis by macrophages. The number of ingested particles per 100 mps was determined for triplicate samples for each condition and expressed as the phagocytic index. Lactating animals are particularly susceptible to mastitis during the early stages of mammary gland involution following weaning. Phagocyte, type of cell that has the ability to ingest, and sometimes digest, foreign particles, such as bacteria, carbon, dust, or dye.
In vitro phagocytic study of blood leucocytes and peritoneal. Phagocytosis is the process of taking in particles such as bacteria, parasites, dead host cells, and cellular and foreign debris by a cell. Phagocytic index definition of phagocytic index by. Trem2 and apoe are implicated in lateonset alzheimers disease. These pseudopodia then fuse, enclosing the microbe win a cytoplasmic vacuole called a phagosome. Index, in the roman catholic church, list of publications forbidden to be read, called index librorum prohibitorum list of forbidden books. The phagocytic index pi or binding index bi was calculated as above from the whole population m3 because essentially all cells had phagocytosed or bound bacteria. Stronger in vitro phagocytosis by monocytesmacrophages is. If your access is via an institutional subscription, please contact your librarian to request reinstatement.
Once a white cell has left the blood vessel and migrated to the enemy, the next job is to eat the microbe. Reticuloendothelial phagocytic clearance as an index of host response to intestinal ischemic shock and therapy you will receive an email whenever this article is corrected, updated, or cited in the literature. Experimental studies of dependence of the phagocytic index on igg concentration revealed a peculiar aspect of this process that was difficult to explain. Reactive astrocytes function as phagocytes after brain. Phagocytic development in the rat pubmed central pmc. Multiple antibiotic resistance indexing of food borne pathogens isolated from. A cell, especially a macrophage or neutrophil of the immune system, that has the ability to engulf and destroy pathogens, waste material, and other. Critical role of galectin3 in phagocytosis by macrophages jci. Please make sure to upload the whole publication to your server then test the link, for more information about testing the links locally. Access to paid content on this site is currently suspended due to excessive activity being detected from your ip address 40. In this study we compared the phagocytic capacity of cells collected from sheep mammary secretions at different stages of involution. Dependence of macrophage phagocytic efficacy on antibody. Meaning, pronunciation, translations and examples log in dictionary. Neutrophils pmns plated onto a layer of yeast particles.
In the present study, the restoration of immunity is characterized by rise in dth response, ha titer and percentage neutrophil adhesion, phagocytic index and lymphoid organ weights in cp induced immunosuppressed rats. The phagocytic index of each prepara tion is the number of organisms ingested by 100 neutro phil polymorphs expressed as a percentage of. Decreased phagocytic function in neutrophils and monocytes. Ingestion of microorganisms and particulate matter by. Barthel index an objective, standardized tool for measuring functional status. Neutrophil phagocytic index pi was calculated as the number of neutrophils associated with reporter beads. Once captured, phagocytes rapidly ingest engulf the microbes. Author links open overlay panel nick platt paul fineran. Nimrod, a putative phagocytosis receptor with egf repeats. Phagocyte definition of phagocyte by merriamwebster. Drosophila gata factor serpent establishes phagocytic. Phagocytosis from ancient greek phagein, meaning to eat, and, kytos, meaning cell is the process by which a cell uses its plasma membrane to engulf a large particle. Download free acrobat reader dc software, the only pdf viewer that lets you read, search, print, and interact with virtually any type of pdf file.
Nimrod, a putative phagocytosis receptor with egf repeats in drosophila plasmatocytes. Total hemocyte count, phagocytic activity and phagocytic index, and serum antioxidant activity were determined to assess innate immune system function and oxidative stress. Phagocytosis of apoptotic cells by macrophages and dendritic cells is necessary for clearance. Examination of newly forming, prephagocytic lesions suggests that oligodendrocyte death underpins the subsequent events that manifest pathologically as active demyelination. The cell membrane of the phagocyte forms fingerlike extensions, called pseudopodia, that surrounds the microbe. Loss of either trem2 or apoe causes dysregulated cholesterol transport and metabolism in microglia. The sample included 30 subjects with severe periodontitis and 27 control subjects without periodontal disease. The macrophage is using its internal cytoskeleton to envelop a cell of the fungus candida albicans. The monocytesmacrophages phagocytic index, phagocytic product, and.
Measuring the phagocytic activity of cells sciencedirect. Splenic phagocytic function after partial splenectomy and. Phagocytic index legal definition of phagocytic index. Links to pubmed are also available for selected references. After the indicated time periods, unbound srbcs were removed and the cells were fixed for phasecontrast microscopy. Reticuloendothelial phagocytic clearance as an index of. Phagocyte definition is a cell such as a macrophage or neutrophil that engulfs and consumes foreign material such as microorganisms and debris such as dead tissue cells. The phagocytic index phi was calculated as the mean number of adheredingested saccharomyces cerevisiae per phagocytozing monocyte or neutrophil multiplied by the percentage of phagocytes involved in. The phagocytic process can be separated into several major stages. Phagocytic index medical definition merriamwebster. Pdf engulfment and destruction of invading microorganisms by phagocytosis are critical components of the. For full access to this pdf, sign in to an existing account, or purchase an annual subscription.
Phagocytic article about phagocytic by the free dictionary. In vitro test of macrophage phagocytic activity of extracts and. Phagocytic recognition of bone by macrophages chambers. The phagocytic index was calculated by geometric mean of fluorescence intensity multiplied by the percentage of fluorescentpositive cells. Alternatively, a phagocytic index can be scored by multiplying the. Phagocyticly definition of phagocyticly by the free. To confirm the interaction of blood neutrophils and the intraphagosomal reporter beads during the assay, illustrative confocal images and timelapse video were also provided in additional file 1.
The pdf file you selected should load here if your web browser has a pdf reader plugin installed for example, a recent version of adobe acrobat reader if you would like more information about how to print, save, and work with pdfs, highwire press provides a helpful frequently asked questions about pdfs alternatively, you can download the pdf file directly to your computer, from where it. This human macrophage, like its cousin the neutrophil, is a professional phagocyte or eating cell phago eating, cyte cell. Scavenger receptors and phagocytosis of bacteria and apoptotic cells. They ingest microorganisms and other particulate antigens that are coated with antibody or complement opsonized, a process mediated by specific cellsurface receptors. Phagocytic index definition, the average number of bacteria ingested per phagocyte in an incubated mixture of bacteria, phagocytes, and blood serum.